CBU - Computational Biology Unit

Lipo can analyse polypeptide sequences encoded within the genome of Gram-negative bacteria and report the sequences with a possible lipo-box. The lipo-box is recognised on the basis of the critera given by Lipo.

Frode Berven (C) 2004

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Criteria for separating lipoproteins associated to the inner and outer membrane

In addition, we implemented in the program a rule that separates the lipoproteins that are directed to the OM from those that remain in the IM. This feature relies on mutation studies indicating that an aspartic acid in position +2 in the mature sequence makes the lipoprotein localize to the inner membrane

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